Metabolic responses to polymyxin treatment in acinetobacter baumannii ATCC 19606: integrating transcriptomics and metabolomics with genome-scale metabolic modeling

Multidrug-resistant (MDR) Acinetobacter baumannii has emerged as a very problematic pathogen over the past decades, with a high incidence in nosocomial infections. Discovered in the late 1940s but abandoned in the 1970s, polymyxins (i.e., polymyxin B and colistin) have been revived as the last-line...

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Bibliographic Details
Main Authors: Zhu, Yan, Zhao, Jinxin, Mahamad Maifiah, Mohd Hafidz, Velkov, Tony, Schreiber, Falk, Lia, Jian
Format: Article
Language:English
English
Published: American Society for Microbiology 2019
Subjects:
Online Access:http://irep.iium.edu.my/70940/
http://irep.iium.edu.my/70940/
http://irep.iium.edu.my/70940/
http://irep.iium.edu.my/70940/7/70940_Metabolic%20Responses%20to%20Polymyxin_wos.pdf
http://irep.iium.edu.my/70940/13/70940_%20Metabolic%20responses%20to%20polymyxin%20treatment%20in%20acinetobacter%20baumannii%20ATCC%2019606.pdf