Influence of artocarpus altilis fruit extract on cancer cell

Conventional chemopreventive agents causes adverse side effects in cancer patients. Thus, this study focuses on the effects of natural plant extract against cancer cell as a way to reduce or detrimental effects of orthodox drugs. The present study emphasizes on anti-cancer potentiality of Artocarpus...

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Main Authors:	Ganeson, Suhassni, Abdul Jamil, Muhammad Mahadi, Ambar, Radzi, Abdul Wahab, Ridhwan
Format:	Conference or Workshop Item
Language:	English English
Published:	Institute of Electrical and Electronics Engineers Inc. 2019
Subjects:	R Medicine (General) RC0254 Neoplasms. Tumors. Oncology (including Cancer)
Online Access:	http://irep.iium.edu.my/72557/ http://irep.iium.edu.my/72557/ http://irep.iium.edu.my/72557/ http://irep.iium.edu.my/72557/1/72557_Influence%20of%20artocarpus%20altilis%20fruit.pdf http://irep.iium.edu.my/72557/2/72557_Influence%20of%20artocarpus%20altilis%20fruit_SCOPUS.pdf

id	iium-72557
recordtype	eprints
spelling	iium-725572019-06-12T03:22:16Z http://irep.iium.edu.my/72557/ Influence of artocarpus altilis fruit extract on cancer cell Ganeson, Suhassni Abdul Jamil, Muhammad Mahadi Ambar, Radzi Abdul Wahab, Ridhwan R Medicine (General) RC0254 Neoplasms. Tumors. Oncology (including Cancer) Conventional chemopreventive agents causes adverse side effects in cancer patients. Thus, this study focuses on the effects of natural plant extract against cancer cell as a way to reduce or detrimental effects of orthodox drugs. The present study emphasizes on anti-cancer potentiality of Artocarpus altilis fruit extract against cervical cancer cell. Cervical cancer cell treated with methanol extract of artocarpus altilis fruit with the concentration varied from 10μg/ml, 20μg/ml, 30μg/ml, 40μg/ml and 50μg/ml. Treated and untreated (cells without treatment) cell proliferation and half maximal inhibitory concentration IC50 measured after 72 hours of incubation. Cells without treatment, 10μg/ml, 20μg/ml, 30μg/ml, 40μg/ml and 50 μg/ml of extract concentration showed 1.3, 0.98, 0.72, 0.65, 0.51, and 0.3 of cell proliferation factor accordingly with 40μg/ml of IC50 value. The result shows that artocarpus altilis is capable in opposing cervical cancer cell proliferation or growth as the proliferation factor decreases with the increasing dose of extract concentration which can be attributed to the presence of bioactive compound in Artocarpus altilis. Institute of Electrical and Electronics Engineers Inc. 2019-03-01 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/72557/1/72557_Influence%20of%20artocarpus%20altilis%20fruit.pdf application/pdf en http://irep.iium.edu.my/72557/2/72557_Influence%20of%20artocarpus%20altilis%20fruit_SCOPUS.pdf Ganeson, Suhassni and Abdul Jamil, Muhammad Mahadi and Ambar, Radzi and Abdul Wahab, Ridhwan (2019) Influence of artocarpus altilis fruit extract on cancer cell. In: 9th IEEE Control and System Graduate Research Colloquium (ICSGRC 2018), 3rd-4th Aug. 2018, Shah Alam, Selangor. https://ieeexplore.ieee.org/document/8657520 10.1109/ICSGRC.2018.8657520
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	R Medicine (General) RC0254 Neoplasms. Tumors. Oncology (including Cancer)
spellingShingle	R Medicine (General) RC0254 Neoplasms. Tumors. Oncology (including Cancer) Ganeson, Suhassni Abdul Jamil, Muhammad Mahadi Ambar, Radzi Abdul Wahab, Ridhwan Influence of artocarpus altilis fruit extract on cancer cell
description	Conventional chemopreventive agents causes adverse side effects in cancer patients. Thus, this study focuses on the effects of natural plant extract against cancer cell as a way to reduce or detrimental effects of orthodox drugs. The present study emphasizes on anti-cancer potentiality of Artocarpus altilis fruit extract against cervical cancer cell. Cervical cancer cell treated with methanol extract of artocarpus altilis fruit with the concentration varied from 10μg/ml, 20μg/ml, 30μg/ml, 40μg/ml and 50μg/ml. Treated and untreated (cells without treatment) cell proliferation and half maximal inhibitory concentration IC50 measured after 72 hours of incubation. Cells without treatment, 10μg/ml, 20μg/ml, 30μg/ml, 40μg/ml and 50 μg/ml of extract concentration showed 1.3, 0.98, 0.72, 0.65, 0.51, and 0.3 of cell proliferation factor accordingly with 40μg/ml of IC50 value. The result shows that artocarpus altilis is capable in opposing cervical cancer cell proliferation or growth as the proliferation factor decreases with the increasing dose of extract concentration which can be attributed to the presence of bioactive compound in Artocarpus altilis.
format	Conference or Workshop Item
author	Ganeson, Suhassni Abdul Jamil, Muhammad Mahadi Ambar, Radzi Abdul Wahab, Ridhwan
author_facet	Ganeson, Suhassni Abdul Jamil, Muhammad Mahadi Ambar, Radzi Abdul Wahab, Ridhwan
author_sort	Ganeson, Suhassni
title	Influence of artocarpus altilis fruit extract on cancer cell
title_short	Influence of artocarpus altilis fruit extract on cancer cell
title_full	Influence of artocarpus altilis fruit extract on cancer cell
title_fullStr	Influence of artocarpus altilis fruit extract on cancer cell
title_full_unstemmed	Influence of artocarpus altilis fruit extract on cancer cell
title_sort	influence of artocarpus altilis fruit extract on cancer cell
publisher	Institute of Electrical and Electronics Engineers Inc.
publishDate	2019
url	http://irep.iium.edu.my/72557/ http://irep.iium.edu.my/72557/ http://irep.iium.edu.my/72557/ http://irep.iium.edu.my/72557/1/72557_Influence%20of%20artocarpus%20altilis%20fruit.pdf http://irep.iium.edu.my/72557/2/72557_Influence%20of%20artocarpus%20altilis%20fruit_SCOPUS.pdf
first_indexed	2023-09-18T21:42:48Z
last_indexed	2023-09-18T21:42:48Z
_version_	1777413252210229248

Influence of artocarpus altilis fruit extract on cancer cell

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