Nitric oxide inhibitory activity and antioxidant evaluations of 2-benzoyl-6-benzylidenecyclohexanone analogs, a novel series of curcuminoid and diarylpentanoid derivatives

Nitric oxide inhibitory activity and antioxidant evaluations of 2-benzoyl-6-benzylidenecyclohexanone analogs, a novel series of curcuminoid and diarylpentanoid derivatives

A series of twenty-four 2-benzoyl-6-benzylidenecyclohexanone analogs were synthesized and evaluated for their nitric oxide inhibition and antioxidant activity. Six compounds (3, 8, 10, 17, 18 and 19) were found to exhibit significant NO inhibitory activity in LPS/IFN-induced RAW 264.7 macrophages,...

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Bibliographic Details
Main Authors: Leong, Sze Wei, Mohd Faudzi, Siti Munirah Mohd Faudzi, Abas, Faridah, Mohd Aluwi, Mohd Fadhlizil Fasihi, Rullah, Kamal, Lam, Kok Wai, Abdul Bahari, Mohd Nazri, Ahmad, Syahida, Tham, Chau Ling, Shaari, Khozirah, Lajis, Nordin H.
Format: Article
Language:English
Published: Elsevier 2015
Subjects:
RS403 Materia Medica-Pharmaceutical Chemistry
Online Access:http://irep.iium.edu.my/73756/
http://irep.iium.edu.my/73756/
http://irep.iium.edu.my/73756/
http://irep.iium.edu.my/73756/1/Kamal%20Rullah%209.pdf

Internet

http://irep.iium.edu.my/73756/
http://irep.iium.edu.my/73756/
http://irep.iium.edu.my/73756/
http://irep.iium.edu.my/73756/1/Kamal%20Rullah%209.pdf

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