Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis

We report a rare case of altered mental status in a young patient with immature ovarian teratoma. A 22-year-old woman presented with seizures, hallucination, amnesia and orofacial dyskinesia. Examination and investigation revealed an ovarian massand asalphing-oophorectomy was performed. The histopat...

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Main Authors:	Lee, CL, Aini Amelia Zainuddin, Abdul Kadir Abdul Karim, Yulianty Arifuddin, Law, Zhee Kang, Md. Isa N, Nor Azlin Mohamed Ismail
Format:	Article
Language:	English
Published:	Faculty of Medicine, UKM Medical Centre 2016
Online Access:	http://journalarticle.ukm.my/9841/ http://journalarticle.ukm.my/9841/ http://journalarticle.ukm.my/9841/1/15._Lee_et_al..pdf

id	ukm-9841
recordtype	eprints
spelling	ukm-98412016-12-14T06:51:00Z http://journalarticle.ukm.my/9841/ Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis Lee, CL Aini Amelia Zainuddin, Abdul Kadir Abdul Karim, Yulianty Arifuddin, Law, Zhee Kang Md. Isa N, Nor Azlin Mohamed Ismail, We report a rare case of altered mental status in a young patient with immature ovarian teratoma. A 22-year-old woman presented with seizures, hallucination, amnesia and orofacial dyskinesia. Examination and investigation revealed an ovarian massand asalphing-oophorectomy was performed. The histopathological examination result showed an immature teratoma grade 2 with thepresence of immature primitive glial tissue. Her CSF N-Methyl-D-Aspartic acid receptor (Anti-NMDAR) antibodytest was positive. N-Methyl-D-Aspartic acid receptor antibody associated limbic encephalitis is an autoimmune antibody-mediated neuropsychiatric disorder. Resection of the tumour and immunotherapy resulted in full recovery. Faculty of Medicine, UKM Medical Centre 2016 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/9841/1/15._Lee_et_al..pdf Lee, CL and Aini Amelia Zainuddin, and Abdul Kadir Abdul Karim, and Yulianty Arifuddin, and Law, Zhee Kang and Md. Isa N, and Nor Azlin Mohamed Ismail, (2016) Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis. Journal of Surgical Academia, 6 (1). pp. 66-69. ISSN 2231-7481 http://jsurgacad.com/toc/6/1
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Kebangasaan Malaysia
building	UKM Institutional Repository
collection	Online Access
language	English
description	We report a rare case of altered mental status in a young patient with immature ovarian teratoma. A 22-year-old woman presented with seizures, hallucination, amnesia and orofacial dyskinesia. Examination and investigation revealed an ovarian massand asalphing-oophorectomy was performed. The histopathological examination result showed an immature teratoma grade 2 with thepresence of immature primitive glial tissue. Her CSF N-Methyl-D-Aspartic acid receptor (Anti-NMDAR) antibodytest was positive. N-Methyl-D-Aspartic acid receptor antibody associated limbic encephalitis is an autoimmune antibody-mediated neuropsychiatric disorder. Resection of the tumour and immunotherapy resulted in full recovery.
format	Article
author	Lee, CL Aini Amelia Zainuddin, Abdul Kadir Abdul Karim, Yulianty Arifuddin, Law, Zhee Kang Md. Isa N, Nor Azlin Mohamed Ismail,
spellingShingle	Lee, CL Aini Amelia Zainuddin, Abdul Kadir Abdul Karim, Yulianty Arifuddin, Law, Zhee Kang Md. Isa N, Nor Azlin Mohamed Ismail, Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis
author_facet	Lee, CL Aini Amelia Zainuddin, Abdul Kadir Abdul Karim, Yulianty Arifuddin, Law, Zhee Kang Md. Isa N, Nor Azlin Mohamed Ismail,
author_sort	Lee, CL
title	Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis
title_short	Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis
title_full	Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis
title_fullStr	Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis
title_full_unstemmed	Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis
title_sort	anti n-methyl-d-aspartate receptor encephalitis with ovarian teratoma: a dilemma in diagnosis
publisher	Faculty of Medicine, UKM Medical Centre
publishDate	2016
url	http://journalarticle.ukm.my/9841/ http://journalarticle.ukm.my/9841/ http://journalarticle.ukm.my/9841/1/15._Lee_et_al..pdf
first_indexed	2023-09-18T19:55:51Z
last_indexed	2023-09-18T19:55:51Z
_version_	1777406523545223168

Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis

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