Colchicine Prodrugs and Codrugs: Chemistry and Bioactivities

Antimitotic colchicine possesses low therapeutic index due to high toxicity effects in non-target cell. However, diverse colchicine analogs have been derivatized as intentions for toxicity reduction and structure-activity relationship (SAR) studying. Hybrid system of colchicine structure with nont...

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Bibliographic Details
Main Authors: Ghawanmeh, Abdullah A., K. F., Chong, Sarkar, Shaheen M., Muntaz, Abu Bakar, Rizafizah, Othaman, Rozida, M. Khalid
Format: Article
Language:English
Published: Elsevier 2018
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/19831/
http://umpir.ump.edu.my/id/eprint/19831/
http://umpir.ump.edu.my/id/eprint/19831/
http://umpir.ump.edu.my/id/eprint/19831/8/fist-2017-kwok-Colchicine%20prodrugs%20and%20codrugs1.pdf